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Mepergan is the brand name for meperidine and promethazine. It is also available under the brand name Meprozine. The meperidine in Mepergan is a narcotic pain reliever, while the promethazine is an anti-nausea medication. When the two medications are combined, they are used to treat moderate to severe pain and have also been used to help a patient to feel calmer before or after surgery.

In the Mepergan, meperidine acts on specific centers in the brain to provide relief from pain. At the same time, the promethazine is an antihistamine that acts with other parts of the brain to decrease anxiety and nausea. The drug is sometimes known on the street as MPTP, the new heroin, MPPP and synthetic heroin.

Abuses of Mepergan

Mepergan does present the potential for addiction and abuse as the meperidine in the drug can produce the same dependence as morphine. The repeated administration of the drug can result in psychic dependence, physical dependence and tolerance. Mepergan is subject to the provisions of the federal narcotics laws.

As patients and other users can quickly build a tolerance for the drug, they may require more of the Mepergan to achieve the same effect. Signs of dependency and abuse include a strong desire or need to continue taking more of the medicine; a need to increase the dose to maintain the effects of the medicine; and withdrawal symptoms occurring after the patient stops taking the medication.

Effects of Mepergan

The effects of Mepergan can be felt 10 to 15 minutes after it is ingested and will typically last anywhere from two to four hours. While the effects are similar to that of morphine, Mepergan also offers sedation, respiratory depression and euphoria that tend to be less intense than morphine.

Using Mepergan can also result in adverse reactions, even when given under the care of a physician. Allergic reactions can include hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Serious side effects can include such symptoms as fast, slow, or uneven heartbeats; shallow breathing; extreme weakness or drowsiness; feeling light-headed, fainting; feeling anxious or agitated; urinating less than usual; tremors; or unusual thoughts or behavior.

Withdrawal of Mepergan

Continuous or prolonged use of Mepergan can create a physical dependence on or tolerance of the drug. If the drug is stopped abruptly, patients with a physical dependence or those who have been taking the drug for a prolonged period of time can experience intense symptoms of withdrawal.

Withdrawal symptoms associated with Mepergan use can occur four to five hours after the last dose and can include, but are not limited to:

• severe anxiety

• insomnia

• profuse sweating

• muscle spasms

• chills

• shivering

• tremors

Treatment of Mepergan Addiction

Mepergan users should taper off the medication slowly under the care of a board-certified physician and board-certified addiction psychiatrist. To ensure the individual rids their body of the drug completely and have a better chance of staying off the drug in the future, entering a treatment center for a 24/7 comfortable detox treatment is highly recommended.

A quality treatment center will do a full physical on a patient and have a board-certified addiction psychiatrist determine the right medications for comfortable detox. This method is used to correct the chemical imbalances in the individual suffering with a Mepergan addiction and should be combined with psychological evaluations and other medical care to address cravings for the drug.

Posted on Nov 19, 2009

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